Il10 (NM_010548) Mouse Recombinant Protein

• Background:

  This gene encodes an anti-inflammatory cytokine that is a member of the class-2 cytokine family. The encoded protein is secreted by cells of both the innate and adaptive immune systems and is crucial for limiting the immune response to a broad range of pathogens. It also has been shown to suppress autoimmune responses. This protein mediates it's immunosuppressive signal through a specific interleukin 10 receptor complex. Aberrant functioning of this gene is associated with numerous immune disorders including graft-versus-host disease, and increased susceptibility to HIV-1 infection and rheumatoid arthritis. [provided by RefSeq, Sep 2015]

• Synonyms:

  CSIF; If2a; IL-; Il-10

• Gene ID:

  16153

• UniProt:

  P18893, Q3U879

• Accession Number mRNA:

  NM_010548

• Chromosomal Location:

  1 56.89 cM

• Expression System:

  HEK293T

• Tag:

  C-MYC/DDK

• Concentration:

  >50 ug/mL as determined by microplate BCA method

• Purity:

  > 80% as determined by SDS-PAGE and Coomassie blue staining

• Form:

  Liquid

• Buffer:

  25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

• Molecular Weight:

  21.1 kDa

• Storage Conditions:

  Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

• Symbol:

  Il10

• Species:

  Mouse

• Protein ID:

  NP_034678

• Overview:

  Purified recombinant protein of Mouse interleukin 10 (Il10), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/16153

• Uniprot URL:

  https://www.uniprot.org/uniprot/P18893

• Accession Number mRNA URL:

  https://www.ncbi.nlm.nih.gov/nuccore/NM_010548

• Protein ID Link:

  https://www.ncbi.nlm.nih.gov/nuccore/NP_034678