Ccl5 (NM_013653) Mouse Recombinant Protein

• Background:

  Chemoattractant for blood monocytes, memory T-helper cells and eosinophils. Causes the release of histamine from basophils and activates eosinophils. May activate several chemokine receptors including CCR1, CCR3, CCR4 and CCR5. May also be an agonist of the G protein-coupled receptor GPR75. Together with GPR75, may play a role in neuron survival through activation of a downstream signaling pathway involving the PI3, Akt and MAP kinases. By activating GPR75 may also play a role in insulin secretion by islet cells.[UniProtKB/Swiss-Prot Function]

• Synonyms:

  MuRantes; RANTES; Scya5; SISd; TCP228

• Gene ID:

  20304

• UniProt:

  P30882, Q5XZF2

• Accession Number mRNA:

  NM_013653

• Chromosomal Location:

  11 50.66 cM

• Expression System:

  HEK293T

• Tag:

  C-MYC/DDK

• Concentration:

  >50 ug/mL as determined by microplate BCA method

• Purity:

  > 80% as determined by SDS-PAGE and Coomassie blue staining

• Form:

  Liquid

• Buffer:

  25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

• Molecular Weight:

  10.5 kDa

• Storage Conditions:

  Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

• Symbol:

  Ccl5

• Species:

  Mouse

• Protein ID:

  NP_038681

• Overview:

  Purified recombinant protein of Mouse chemokine (C-C motif) ligand 5 (Ccl5), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/20304

• Uniprot URL:

  https://www.uniprot.org/uniprot/P30882

• Accession Number mRNA URL:

  https://www.ncbi.nlm.nih.gov/nuccore/NM_013653

• Protein ID Link:

  https://www.ncbi.nlm.nih.gov/nuccore/NP_038681