PD L2 (PDCD1LG2) (NM_025239) Human Recombinant Protein

• Background:

  Involved in the costimulatory signal, essential for T-cell proliferation and IFNG production in a PDCD1-independent manner. Interaction with PDCD1 inhibits T-cell proliferation by blocking cell cycle progression and cytokine production (By similarity) .[UniProtKB/Swiss-Prot Function]

• Synonyms:

  B7DC; bA574F11.2; Btdc; CD273; PD-L2; PDCD1L2; PDL2

• Gene ID:

  80380

• UniProt:

  Q9BQ51

• Accession Number mRNA:

  NM_025239

• Chromosomal Location:

  9p24.1

• Expression System:

  HEK293

• Tag:

  C-Fc

• Related Pathways:

  Cell adhesion molecules (CAMs)

• Field of Research:

  Cell adhesion molecules (CAMs)

• Concentration:

  >50 ug/mL as determined by microplate BCA method

• Purity:

  > 80% as determined by SDS-PAGE and Coomassie blue staining

• Form:

  Liquid

• Buffer:

  PBS, pH7.4, 10% glycerol

• Function:

  Transmembrane

• Molecular Weight:

  50 kDa

• Storage Conditions:

  Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

• Symbol:

  PDCD1LG2

• Species:

  Human

• Protein ID:

  NP_079515

• Overview:

  Purified recombinant protein of human programmed cell death 1 ligand 2 (PDCD1LG2), extracellular domain with C-terminal Fc fusion, expressed in human cells, 20 µg

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/80380

• Uniprot URL:

  https://www.uniprot.org/uniprot/Q9BQ51

• Accession Number mRNA URL:

  https://www.ncbi.nlm.nih.gov/nuccore/NM_025239

• Protein ID Link:

  https://www.ncbi.nlm.nih.gov/nuccore/NP_079515