PDCD1LG2 Antibody (N-term) [AMM22278G]

• Background:

  Tissue Location: Highly expressed in heart, placenta, pancreas, lung and liver and weakly expressed in spleen, lymph nodes and thymus

• Synonyms:

  Programmed cell death 1 ligand 2, PD-1 ligand 2, PD-L2, PDCD1 ligand 2, Programmed death ligand 2, Butyrophilin B7-DC, B7-DC, CD273, PDCD1LG2, B7DC, CD273, PDCD1L2, PDL2

• Gene Name:

  PDCD1LG2

• Gene ID:

  80380

• UniProt:

  Q9BQ51

• Chromosomal Location:

  [Isoform 3]: Secreted [Isoform 1]: Cell membrane; Single-pass type I membrane protein {ECO:0000250|UniProtKB:Q9WUL5, ECO:0000305|PubMed:15340161}

• Applications:

  WB, IHC-P

• Dilution:

  IHC-P--1:100~500 WB--1:8000

• Function:

  Involved in the costimulatory signal, essential for T-cell proliferation and IFNG production in a PDCD1-independent manner. Interaction with PDCD1 inhibits T-cell proliferation by blocking cell cycle progression and cytokine production (By similarity) .

• Molecular Weight:

  30957

• Storage Conditions:

  Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

• Overview:

  We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality PDCD1LG2 Antibody (N-term) [AMM22278G].

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/?term=80380

• Uniprot URL:

  https://www.uniprot.org/uniprot/Q9BQ51