SLC25A13 (NM_014251) Human Recombinant Protein

• Background:

  This gene is a member of the mitochondrial carrier family. The encoded protein contains four EF-hand Ca (2+) binding motifs in the N-terminal domain, and localizes to mitochondria. The protein catalyzes the exchange of aspartate for glutamate and a proton across the inner mitochondrial membrane, and is stimulated by calcium on the external side of the inner mitochondrial membrane. Mutations in this gene result in citrullinemia, type II. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2009]

• Synonyms:

  ARALAR2; CITRIN; CTLN2; NICCD

• Gene ID:

  10165

• UniProt:

  Q9UJS0

• Accession Number mRNA:

  NM_014251

• Chromosomal Location:

  7q21.3

• Expression System:

  E. coli

• Tag:

  N-His

• Concentration:

  >50 ug/mL as determined by microplate BCA method

• Purity:

  > 80% as determined by SDS-PAGE and Coomassie blue staining

• Form:

  Liquid

• Buffer:

  25mM Tris, pH8.0, 150mM NaCl, 10% glycerol, 1 % Sarkosyl.

• Function:

  Druggable Genome

• Molecular Weight:

  74 kDa

• Storage Conditions:

  Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

• Symbol:

  SLC25A13

• Species:

  Human

• Protein ID:

  NP_055066

• Overview:

  Purified recombinant protein of Human solute carrier family 25, member 13 (citrin) (SLC25A13), nuclear gene encoding mitochondrial protein, transcript variant 2, full length, with N-terminal HIS tag, expressed in E. coli, 50ug

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/10165

• Uniprot URL:

  https://www.uniprot.org/uniprot/Q9UJS0

• Accession Number mRNA URL:

  https://www.ncbi.nlm.nih.gov/nuccore/NM_014251

• Protein ID Link:

  https://www.ncbi.nlm.nih.gov/nuccore/NP_055066