TFEC (NM_001018058) Human Recombinant Protein

• Background:

  This gene encodes a member of the micropthalmia (MiT) family of basic helix-loop-helix leucine zipper transcription factors. MiT transcription factors regulate the expression of target genes by binding to E-box recognition sequences as homo- or heterodimers, and play roles in multiple cellular processes including survival, growth and differentiation. The encoded protein is a transcriptional activator of the nonmuscle myosin II heavy chain-A gene, and may also co-regulate target genes in osteoclasts as a heterodimer with micropthalmia-associated transcription factor. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Sep 2011]

• Synonyms:

  BHLHe34; hTFEC-L; TCFEC; TFE-C; TFEC-L; TFECL

• Gene ID:

  22797

• UniProt:

  O14948

• Accession Number mRNA:

  NM_001018058

• Chromosomal Location:

  7q31.2

• Expression System:

  E. coli

• Tag:

  N-His

• Concentration:

  >50 ug/mL as determined by microplate BCA method

• Purity:

  > 80% as determined by SDS-PAGE and Coomassie blue staining

• Form:

  Liquid

• Buffer:

  25mM Tris, pH8.0, 150mM NaCl, 10% glycerol, 1 % Sarkosyl.

• Function:

  Druggable Genome, Transcription Factors

• Molecular Weight:

  35.4 kDa

• Storage Conditions:

  Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

• Symbol:

  TFEC

• Species:

  Human

• Protein ID:

  NP_001018068

• Overview:

  Purified recombinant protein of Human transcription factor EC (TFEC), transcript variant 2, full length, with N-terminal HIS tag, expressed in E. coli, 50ug

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/22797

• Uniprot URL:

  https://www.uniprot.org/uniprot/O14948

• Accession Number mRNA URL:

  https://www.ncbi.nlm.nih.gov/nuccore/NM_001018058

• Protein ID Link:

  https://www.ncbi.nlm.nih.gov/nuccore/NP_001018068