EOMES (NM_005442) Human Recombinant Protein

• Background:

  This gene belongs to the TBR1 (T-box brain protein 1) sub-family of T-box genes that share the common DNA-binding T-box domain. The encoded protein is a transcription factor which is crucial for embryonic development of mesoderm and the central nervous system in vertebrates. The protein may also be necessary for the differentiation of effector CD8+ T cells which are involved in defense against viral infections. A similar gene disrupted in mice is shown to be essential during trophoblast development and gastrulation. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2013]

• Synonyms:

  TBR2

• Gene ID:

  8320

• UniProt:

  O95936, B7Z4K0

• Accession Number mRNA:

  NM_005442

• Chromosomal Location:

  3p24.1

• Expression System:

  E. coli

• Tag:

  N-His

• Concentration:

  >50 ug/mL as determined by microplate BCA method

• Purity:

  > 80% as determined by SDS-PAGE and Coomassie blue staining

• Form:

  Liquid

• Buffer:

  50mM Tris, 8M Urea, pH8.0.

• Function:

  Embryonic stem cells, ES Cell Differentiation/IPS, Transcription Factors

• Molecular Weight:

  72.6 kDa

• Storage Conditions:

  Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

• Symbol:

  EOMES

• Species:

  Human

• Protein ID:

  NP_005433

• Overview:

  Purified recombinant protein of Human eomesodermin (EOMES), full length, with N-terminal HIS tag, expressed in E. coli, 50ug

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/8320

• Uniprot URL:

  https://www.uniprot.org/uniprot/O95936

• Accession Number mRNA URL:

  https://www.ncbi.nlm.nih.gov/nuccore/NM_005442

• Protein ID Link:

  https://www.ncbi.nlm.nih.gov/nuccore/NP_005433