XAF1 (NM_017523) Human Recombinant Protein

• Background:

  This gene encodes a protein which binds to and counteracts the inhibitory effect of a member of the IAP (inhibitor of apoptosis) protein family. IAP proteins bind to and inhibit caspases which are activated during apoptosis. The proportion of IAPs and proteins which interfere with their activity, such as the encoded protein, affect the progress of the apoptosis signaling pathway. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2012]

• Synonyms:

  BIRC4BP; HSXIAPAF1; XIAPAF1

• Gene ID:

  54739

• UniProt:

  Q6GPH4

• Accession Number mRNA:

  NM_017523

• Chromosomal Location:

  17p13.1

• Expression System:

  E. coli

• Tag:

  N-GST and C-His

• Concentration:

  >50 ug/mL as determined by microplate BCA method

• Purity:

  > 80% as determined by SDS-PAGE and Coomassie blue staining

• Form:

  Liquid

• Buffer:

  25mM Tris, pH8.0, 150mM NaCl, 10% glycerol, 1%Sarkosyl.

• Molecular Weight:

  62.4 kDa

• Storage Conditions:

  Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

• Symbol:

  XAF1

• Species:

  Human

• Protein ID:

  NP_059993

• Overview:

  Purified recombinant protein of Human XIAP associated factor 1 (XAF1), transcript variant 1, full length, with N-terminal GST and C-terminal His tag, expressed in E. coli, 50ug

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/54739

• Uniprot URL:

  https://www.uniprot.org/uniprot/Q6GPH4

• Accession Number mRNA URL:

  https://www.ncbi.nlm.nih.gov/nuccore/NM_017523

• Protein ID Link:

  https://www.ncbi.nlm.nih.gov/nuccore/NP_059993