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Recombinant Mouse IL-7 Protein

CAT: 0882-PM0016E2Size: 20 µgDry Ice: NoHazardous: No
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CAT#:0882-PM0016E2Size:20 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
The target cells of IL-7 are mainly lymphocytes, and have growth-promoting activities against B progenitor cells derived from human or mouse bone marrow, thymocytes, and peripheral mature T cells. Synergistic with stem cell growth factor (SCF) can stimulate mitosis of b precursor, which can be inhibited by tgf and inhibited; but has no significant effect on the growth of progenitor B (pro-b) . Promote the maturation of double-negative thymocytes, and provide the initial signal of tcr gene recombination during embryonic thymocyte development; however, it has no obvious effect on mature T cells. Inducing thymocytes or peripheral blood lymphocytes to produce LAK cell activity, the effector cells are mainly CD8+ subpopulations; however, IL-7-induced LAK cells do not have NK activity.IL-7 can stimulate myeloid precursor cells and megakaryocytes to produce colony forming units and platelets, which can restore the body from the immunosuppressive effect of cyclophosphamide; at higher concentrations, IL-7 can also enhance macrophages. Cytotoxic activity, induces monocyte secretion of cytokines.
Purity
Greater than 95% by SDS-PAGE
Form
Lyophilized
Buffer
0.2 μm filtered PBS, pH7.4
Storage Conditions
-70°C

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