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POMP Rabbit pAb (APR28502N)

CAT: 0882-APR28502N-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:0882-APR28502N-01Size:50 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
The protein encoded by this gene is a molecular chaperone that binds 20S preproteasome components and is essential for 20S proteasome formation. The 20S proteasome is the proteolytically active component of the 26S proteasome complex. The encoded protein is degraded before the maturation of the 20S proteasome is complete. A variant in the 5' UTR of this gene has been associated with KLICK syndrome, a rare skin disorder.
Overview
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality POMP Rabbit pAb (APR28502N) .
Synonyms
POMP; C13orf12; HSPC014; PNAS-110; UMP1
Gene ID
51371
UniProt
Q9Y244
Cellular Locus
Cytoplasm, Microsome membrane, Nucleus, cytosol
Dilution
WB 1:500 - 1:1000
Form
Liquid
Buffer
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Molecular Weight
Calculated MW: 15kDa Observed MW: 16kDa
Storage Conditions
Store at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
Gene ID URL
https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=51371
Uniprot URL
https://www.uniprot.org/uniprot/Q9Y244
AA Sequence
MNARGLGSELKDSIPVTELSASGPFESHDLLRKGFSCVKNELLPSHPLELSEKNFQLNQDKMNFSTLRNIQGLFAPLKLQMEFKAVQQVQRLPFLSSSNLSLDVLRGNDETIGFEDILNDPSQSEVMGEPHLMVEYKLGLL

UniProtKB · Q9Y244

Proteasome maturation protein

POMP_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
Q9Y244
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
POMP
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
—
Processing
—
Secondary accessions
A5HKJ2, D6MXU3, Q9HB69
Protein keywords

Technical term

3D-structureDirect protein sequencingProteomics identificationReference proteome

Molecular function

Chaperone

Cellular component

CytoplasmEndoplasmic reticulumMembraneMicrosomeNucleus

Disease

IchthyosisPalmoplantar keratoderma

PTM

Isopeptide bondUbl conjugation

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