CD2AP Rabbit pAb (APR27700N)

CAT: 0882-APR27700N-01Size: 50 µLDry Ice: NoHazardous: No

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CAT#:0882-APR27700N-01Size:50 µL

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24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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Background

This gene encodes a scaffolding molecule that regulates the actin cytoskeleton. The protein directly interacts with filamentous actin and a variety of cell membrane proteins through multiple actin binding sites, SH3 domains, and a proline-rich region containing binding sites for SH3 domains. The cytoplasmic protein localizes to membrane ruffles, lipid rafts, and the leading edges of cells. It is implicated in dynamic actin remodeling and membrane trafficking that occurs during receptor endocytosis and cytokinesis. Haploinsufficiency of this gene is implicated in susceptibility to glomerular disease.

Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality CD2AP Rabbit pAb (APR27700N) .

Synonyms

CD2AP; CMS

Gene ID

23607

UniProt

Q9Y5K6

Cellular Locus

Cell projection, Cytoplasm, cytoskeleton, ruffle

Dilution

WB 1:500 - 1:2000

Form

Liquid

Buffer

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Molecular Weight

Calculated MW: 71kDa Observed MW: 90kDa

Storage Conditions

Store at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Gene ID URL

https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=23607

Uniprot URL

https://www.uniprot.org/uniprot/Q9Y5K6

AA Sequence

Email for sequence

UniProtKB · Q9Y5K6

CD2-associated protein

CD2AP_HUMAN · Homo sapiens

View on UniProt ↗

Primary accession: Q9Y5K6
Review status: UniProtKB reviewed (Swiss-Prot)
Gene: CD2AP
Protein existence: 1: Evidence at protein level
Organism: Homo sapiens (Human)
Taxonomy ID: 9606
Alternative names: —
EC number: —
Processing: —
Secondary accessions: A6NL34, Q5VYA3, Q9UG97

Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

Biological process

Cell cycleCell divisionHost-virus interactionMitosis

Cellular component

Cell junctionCell projectionCytoplasmCytoskeleton

Domain

Coiled coilRepeatSH3 domainSH3-binding

PTM

Isopeptide bondPhosphoproteinUbl conjugation

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