DCD Rabbit pAb (APR27253N)

CAT: 0882-APR27253N-01Size: 50 µLDry Ice: NoHazardous: No

1 / 1

CAT#:0882-APR27253N-01Size:50 µL

Selected

24/48H Stock Items & 2 to 6 Weeks non Stock Items.

Quick Request Actions

Background

This antimicrobial gene encodes a secreted protein that is subsequently processed into mature peptides of distinct biological activities. The C-terminal peptide is constitutively expressed in sweat and has antibacterial and antifungal activities. The N-terminal peptide, also known as diffusible survival evasion peptide, promotes neural cell survival under conditions of severe oxidative stress. A glycosylated form of the N-terminal peptide may be associated with cachexia (muscle wasting) in cancer patients. Alternative splicing results in multiple transcript variants encoding different isoforms.

Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality DCD Rabbit pAb (APR27253N) .

Synonyms

DCD; AIDD; DCD-1; DSEP; HCAP; PIF; dermcidin

Gene ID

117159

UniProt

P81605

Cellular Locus

Secreted

Dilution

WB 1:500 - 1:2000 IF 1:50 - 1:100

Form

Liquid

Buffer

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Molecular Weight

Calculated MW: 8kDa/11kDa/12kDa Observed MW: 11kDa

Storage Conditions

Store at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Gene ID URL

https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=117159

Uniprot URL

https://www.uniprot.org/uniprot/P81605

AA Sequence

YDPEAASAPGSGNPCHEASAAQKENAGEDPGLARQAPKPRKQRSSLLEKGLDGAKKAVGGLGKLGKDAVEDLESVGKGAVHDVKDVLDSVL

UniProtKB · P81605

Dermcidin

DCD_HUMAN · Homo sapiens

View on UniProt ↗

Primary accession: P81605
Review status: UniProtKB reviewed (Swiss-Prot)
Gene: DCD
Protein existence: 1: Evidence at protein level
Organism: Homo sapiens (Human)
Taxonomy ID: 9606
Alternative names: —
EC number: 3.4.-.-
Processing: Precursor
Secondary accessions: A5JHP2, A5JHP3, P58461, Q53YJ2

Protein keywords

Technical term

3D-structureDirect protein sequencingProteomics identificationReference proteome

PTM

AcetylationGlycoproteinProteoglycan

Coding sequence diversity

Alternative splicing

Molecular function

AntibioticAntimicrobialFungicideHydrolaseProtease

Ligand

ManganeseMetal-bindingZinc

Cellular component

MembraneSecreted

Domain

SignalTransmembraneTransmembrane helix

Related Products

Catalog	Name
APR27283N-01	TMLHE Rabbit pAb (APR27283N)
APR27273N-01	RNF7 Rabbit pAb (APR27273N)
APR27263N-01	MID1 Rabbit pAb (APR27263N)
APR27255N-01	GCM1 Rabbit pAb (APR27255N)
APR27243N-01	AKT1 Rabbit pAb (APR27243N)
APR27233N-01	SETD6 Rabbit pAb (APR27233N)
APR24253N-01	PHF6 Rabbit pAb (APR24253N)
APR22753N-01	GPR62 Rabbit pAb (APR22753N)
APR27853N-01	ACSL6 Rabbit pAb (APR27853N)
APR27753N-01	TGS1 Rabbit pAb (APR27753N)

Alternative Products

Catalog	Name
AR05252PU-N	Rabbit IgG Rabbit Protein
AR05110PU-N	Rabbit IgM Rabbit Protein
ES20830-01	ATG14L Rabbit rabbit pAb
ES20829-01	ATG4a Rabbit rabbit pAb
ES20658-01	NM23A Rabbit rabbit pAb
ES20826-01	ATG5 Rabbit rabbit pAb
NBP1-71681	Rabbit Normal Rabbit Serum
RTR500	Rabbit-to-Rabbit Blocking Reagent
ES20827-01	ATG4c Rabbit rabbit pAb
ES20803-01	Calreticulin Rabbit rabbit pAb