EIF5B Rabbit pAb (APR26186N)

CAT: 0882-APR26186N-01Size: 50 µLDry Ice: NoHazardous: No

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CAT#:0882-APR26186N-01Size:50 µL

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24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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Background

Accurate initiation of translation in eukaryotes is complex and requires many factors, some of which are composed of multiple subunits. The process is simpler in prokaryotes which have only three initiation factors (IF1, IF2, IF3) . Two of these factors are conserved in eukaryotes: the homolog of IF1 is eIF1A and the homolog of IF2 is eIF5B. This gene encodes eIF5B. Factors eIF1A and eIF5B interact on the ribosome along with other initiation factors and GTP to position the initiation methionine tRNA on the start codon of the mRNA so that translation initiates accurately.

Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality EIF5B Rabbit pAb (APR26186N) .

Synonyms

EIF5B; IF2

Gene ID

9669

UniProt

O60841

Cellular Locus

Cytoplasm

Dilution

IF 1:10 - 1:100

Form

Liquid

Buffer

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Molecular Weight

Calculated MW: 138kDa

Storage Conditions

Store at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Gene ID URL

https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=9669

Uniprot URL

https://www.uniprot.org/uniprot/O60841

AA Sequence

IRGLLLPPPMKELRVKNQYEKHKEVEAAQGVKILGKDLEKTLAGLPLLVAYKEDEIPVLKDELIHELKQTLNAIKLEEKGVYVQASTLGSLEALLEFLKTSEVPYAGINIGPVHKKDVMKASVMLEHDPQYAVILAFDVRIERDAQEMADSLGVRIFSAEIIYHLFDAFTKYRQDYKKQKQEEFKHIAVFPCKIKILPQYIFNSRDPIVMGVTVEAGQVKQGTPMCVPSKNFVDIGIVTSIEINHKQVDVAKKGQEVCVKIEPIPGESPKMFGRHFEATDILVSKISRQSIDALKDWFRDEMQKSDWQLIVELKKVFEII

UniProtKB · O60841

Eukaryotic translation initiation factor 5B

IF2P_HUMAN · Homo sapiens

View on UniProt ↗

Primary accession: O60841
Review status: UniProtKB reviewed (Swiss-Prot)
Gene: EIF5B
Protein existence: 1: Evidence at protein level
Organism: Homo sapiens (Human)
Taxonomy ID: 9606
Alternative names: eIF-5B
EC number: 3.6.5.3
Processing: —
Secondary accessions: O95805, Q53RV7, Q53SI8, Q9UF81, Q9UMN7

Protein keywords

Technical term

3D-structureDirect protein sequencingProteomics identificationReference proteome

Cellular component

Cytoplasm

Ligand

GTP-bindingMetal-bindingNucleotide-binding

Molecular function

HydrolaseInitiation factor

PTM

Phosphoprotein

Biological process

Protein biosynthesis

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