GOT1 Rabbit pAb (APR26132N)

CAT: 0882-APR26132N-01Size: 50 µLDry Ice: NoHazardous: No

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CAT#:0882-APR26132N-01Size:50 µL

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24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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Background

Glutamic-oxaloacetic transaminase is a pyridoxal phosphate-dependent enzyme which exists in cytoplasmic and mitochondrial forms, GOT1 and GOT2, respectively. GOT plays a role in amino acid metabolism and the urea and tricarboxylic acid cycles. The two enzymes are homodimeric and show close homology.

Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality GOT1 Rabbit pAb (APR26132N) .

Synonyms

GOT1; AST1; ASTQTL1; GIG18; cAspAT; cCAT

Gene ID

2805

UniProt

P17174

Cellular Locus

Cytoplasm

Applications

WB (Mus musculus, Rattus norvegicus)

Dilution

WB 1:500 - 1:2000 IHC 1:50 - 1:200 IF 1:10 - 1:100

Form

Liquid

Buffer

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Molecular Weight

Calculated MW: 44kDa/46kDa Observed MW: 41KDa

Storage Conditions

Store at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Gene ID URL

https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=2805

Uniprot URL

https://www.uniprot.org/uniprot/P17174

AA Sequence

FVSEGFEFFCAQSFSKNFGLYNERVGNLTVVGKEPESILQVLSQMEKIVRITWSNPPAQGARIVASTLSNPELFEEWTGNVKTMADRILTMRSELRARLEALKTPGTWNHITDQIGMFSFTGLNPKQVEYLVNEKHIYLLPSGRINVSGLTTKNLDYVATSIHEAVTKIQ

UniProtKB · P17174

Aspartate aminotransferase, cytoplasmic

AATC_HUMAN · Homo sapiens

View on UniProt ↗

Primary accession: P17174
Review status: UniProtKB reviewed (Swiss-Prot)
Gene: GOT1
Protein existence: 1: Evidence at protein level
Organism: Homo sapiens (Human)
Taxonomy ID: 9606
Alternative names: cAspAT
EC number: 2.6.1.1, 2.6.1.3
Processing: —
Secondary accessions: B2R6R7, B7Z7E9, Q5VW80

Protein keywords

Technical term

3D-structureDirect protein sequencingProteomics identificationReference proteome

Coding sequence diversity

Alternative splicing

Biological process

Amino-acid biosynthesis

Molecular function

AminotransferaseTransferase

Cellular component

Cytoplasm

PTM

Phosphoprotein

Ligand

Pyridoxal phosphate

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