EIF4A3 Rabbit pAb (APR25480N)

CAT: 0882-APR25480N-01Size: 50 µLDry Ice: NoHazardous: No

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CAT#:0882-APR25480N-01Size:50 µL

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24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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Background

This gene encodes a member of the DEAD box protein family. DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure, such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. The protein encoded by this gene is a nuclear matrix protein. Its amino acid sequence is highly similar to the amino acid sequences of the translation initiation factors eIF4AI and eIF4AII, two other members of the DEAD box protein family.

Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality eIF4A3 Rabbit pAb (APR25480N) .

Synonyms

EIF4A3; DDX48; MUK34; NMP265; NUK34; RCPS; eIF4AIII; Fal1

Gene ID

9775

UniProt

P38919

Cellular Locus

Cytoplasm, Nucleus, Nucleus speckle

Dilution

WB 1:1000 - 1:3000 IHC 1:50 - 1:200

Form

Liquid

Buffer

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Molecular Weight

Calculated MW: 46kDa Observed MW: 47kDa

Storage Conditions

Store at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Gene ID URL

https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=9775

Uniprot URL

https://www.uniprot.org/uniprot/P38919

AA Sequence

MATTATMATSGSARKRLLKEEDMTKVEFETSEEVDVTPTFDTMGLREDLLRGIYAYGFEKPSAIQQRAIKQIIKGRDVIAQSQSGTGKTATFSISVLQCLDIQVRETQALILAPTRELAVQIQKGLLALGDYMNVQCHACIGGTNVGEDIRKLDYGQHVVAGTPGRVFDMIRRRSLRTRAIKMLVLDEADEMLNKGFKEQIYDVYRYLPP

UniProtKB · P38919

Eukaryotic initiation factor 4A-III

IF4A3_HUMAN · Homo sapiens

View on UniProt ↗

Primary accession: P38919
Review status: UniProtKB reviewed (Swiss-Prot)
Gene: EIF4A3
Protein existence: 1: Evidence at protein level
Organism: Homo sapiens (Human)
Taxonomy ID: 9606
Alternative names: eIF-4A-III, eIF4A-III
EC number: 3.6.4.13
Processing: —
Secondary accessions: Q15033, Q6IBQ2, Q96A18

Protein keywords

Technical term

3D-structureDirect protein sequencingProteomics identificationReference proteome

PTM

AcetylationIsopeptide bondPhosphoproteinUbl conjugation

Ligand

ATP-bindingNucleotide-binding

Cellular component

CytoplasmNucleusSpliceosome

Disease

Disease variant

Molecular function

HelicaseHydrolaseRNA-binding

Biological process

mRNA processingmRNA splicingmRNA transportNonsense-mediated mRNA decayrRNA processingTranslation regulationTransport

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