TCF12 Rabbit pAb (APR25420N)

CAT: 0882-APR25420N-01Size: 50 µLDry Ice: NoHazardous: No

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CAT#:0882-APR25420N-01Size:50 µL

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24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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Background

The protein encoded by this gene is a member of the basic helix-loop-helix (bHLH) E-protein family that recognizes the consensus binding site (E-box) CANNTG. This encoded protein is expressed in many tissues, among them skeletal muscle, thymus, B- and T-cells, and may participate in regulating lineage-specific gene expression through the formation of heterodimers with other bHLH E-proteins. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been determined.

Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality TCF12 Rabbit pAb (APR25420N) .

Synonyms

TCF12; CRS3; HEB; HTF4; HsT17266; TCF-12; bHLHb20

Gene ID

6938

UniProt

Q99081

Cellular Locus

Nucleus

Dilution

WB 1:200 - 1:1000

Form

Liquid

Buffer

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Molecular Weight

Calculated MW: 48kDa/55kDa/72kDa/75kDa Observed MW: 68kDa

Storage Conditions

Store at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Gene ID URL

https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=6938

Uniprot URL

https://www.uniprot.org/uniprot/Q99081

AA Sequence

PIGSLNSNYGGSSLVASSRSASMVGTHREDSVSLNGNHSVLSSTVTTSSTDLNHKTQENYRGGLQSQSGTVVTTEIKTENKEKDENLHEPPSSDDMKSDDESSQKDIKVSSRGRTSSTNEDEDLNPEQKIEREKERRMANNARERLRVRDINEAFKELGRMCQLHLKSEKPQTKLLILHQAVAVILSLEQQVRERNLNPKAACLKRREEEKVSAVSAEPPTTLPGTHPGLSETTNPMGHM

UniProtKB · Q99081

Transcription factor 12

HTF4_HUMAN · Homo sapiens

View on UniProt ↗

Primary accession: Q99081
Review status: UniProtKB reviewed (Swiss-Prot)
Gene: TCF12
Protein existence: 1: Evidence at protein level
Organism: Homo sapiens (Human)
Taxonomy ID: 9606
Alternative names: TCF-12
EC number: —
Processing: —
Secondary accessions: B4E1W1, Q7Z3D9, Q86TC1, Q86VM2

Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

Coding sequence diversity

Alternative splicing

Disease

CraniosynostosisDisease variantHypogonadotropic hypogonadismKallmann syndrome

Molecular function

Developmental proteinDNA-binding

Biological process

DifferentiationNeurogenesisTranscriptionTranscription regulation

PTM

Isopeptide bondPhosphoproteinUbl conjugation

Cellular component