GRB14 Rabbit pAb (APR24933N)

• Background:

  The product of this gene belongs to a small family of adapter proteins that are known to interact with a number of receptor tyrosine kinases and signaling molecules. This gene encodes a growth factor receptor-binding protein that interacts with insulin receptors and insulin-like growth-factor receptors. This protein likely has an inhibitory effect on receptor tyrosine kinase signaling and, in particular, on insulin receptor signaling. This gene may play a role in signaling pathways that regulate growth and metabolism. Alternative splicing results in multiple transcript variants.

• Synonyms:

  GRB14

• Gene ID:

  2888

• UniProt:

  Q14449

• Cellular Locus:

  Cytoplasm, Endosome membrane, Golgi apparatus membrane, Peripheral membrane protein

• Dilution:

  WB 1:500 - 1:1000 IHC 1:25 - 1:100

• Form:

  Liquid

• Buffer:

  Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

• Molecular Weight:

  Calculated MW: 51kDa/60kDa Observed MW: 61kDa

• Storage Conditions:

  Store at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

• Overview:

  We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality GRB14 Rabbit pAb (APR24933N) .

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=2888

• Uniprot URL:

  https://www.uniprot.org/uniprot/Q14449

• AA Sequence:

  Email for sequence