RNF144A Rabbit pAb (APR23822N)

CAT: 0882-APR23822N-01Size: 50 µLDry Ice: NoHazardous: No

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CAT#:0882-APR23822N-01Size:50 µL

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24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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Background

This gene encodes a member of a family of RING finger domain-containing E3 ubiquitin ligases that also includes parkin and parc. The expression of this gene is induced by DNA damage. The encoded protein interacts with the cytoplasmic DNA-dependent protein kinase, catalytic subunit (DNA-PKcs) and promotes its degradation through ubiquitination. The orthologous mouse protein has been shown to interact with a ubiquitin-conjugating enzyme involved in embryonic development. [provided by RefSeq, Mar 2017]

Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality RNF144A Rabbit pAb (APR23822N) .

Synonyms

RNF144; UBCE7IP4; hUIP4; RNF144A

Gene ID

9781

UniProt

P50876

Dilution

WB 1:500 - 1:2000

Form

Liquid

Buffer

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Molecular Weight

Observed MW: 38kDa

Storage Conditions

Store at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Gene ID URL

https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=9781

Uniprot URL

https://www.uniprot.org/uniprot/P50876

AA Sequence

ELLIKEGLETAISCPDAACPKQGHLQENEIECMVAAEIMQRYKKLQFEREVLFDPCRTWCPASTCQAVCQLQDVGLQTPQPVQCKACRMEFCSTCKASWHPGQGCPETMPITFLPGETSAAFKMEEDD

UniProtKB · P50876

E3 ubiquitin-protein ligase RNF144A

R144A_HUMAN · Homo sapiens

View on UniProt ↗

Primary accession: P50876
Review status: UniProtKB reviewed (Swiss-Prot)
Gene: RNF144A
Protein existence: 1: Evidence at protein level
Organism: Homo sapiens (Human)
Taxonomy ID: 9606
Alternative names: —
EC number: 2.3.2.31
Processing: —
Secondary accessions: D6W4Y6, Q585H5

Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

Cellular component

Cell membraneCytoplasmic vesicleEndoplasmic reticulumEndosomeMembrane

Ligand

Metal-bindingZinc

Domain

RepeatTransmembraneTransmembrane helixZinc-finger

Molecular function

Transferase

PTM

Ubl conjugation

Biological process

Ubl conjugation pathway

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