THSD7A Rabbit pAb (APR23213N)

CAT: 0882-APR23213N-01Size: 50 µLDry Ice: NoHazardous: No

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CAT#:0882-APR23213N-01Size:50 µL

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24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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Background

The protein encoded by this gene is found almost exclusively in endothelial cells from placenta and umbilical cord. The encoded protein appears to interact with alpha (V) beta (3) integrin and paxillin to inhibit endothelial cell migration and tube formation. This protein may be involved in cytoskeletal organization. Variations in this gene may be associated with low bone mineral density in osteoporosis.

Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality THSD7A Rabbit pAb (APR23213N) .

Synonyms

THSD7A

Gene ID

221981

UniProt

Q9UPZ6

Cellular Locus

Cell membrane, Secreted, Single-pass type I membrane protein

Dilution

WB 1:500 - 1:2000

Form

Liquid

Buffer

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Molecular Weight

Calculated MW: 185kDa Observed MW: 260kDa

Storage Conditions

Store at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Gene ID URL

https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=221981

Uniprot URL

https://www.uniprot.org/uniprot/Q9UPZ6

AA Sequence

AAQGEAEAPTLYLWKTGPWGRCMGDECGPGGIQTRAVWCAHVEGWTTLHTNCKQAERPNNQQNCFKVCDWHKELYDWRLGPWNQCQPVISKSLEKPLECIKGEEGIQVREIACIQKDKDIPAEDIICEYFEPKPLLEQACLIPCQQDCIVSEFSAWSECSKTCGSGLQHRTRHVVAPPQFGGSGCPNLTEFQVCQSSPCEAEELRYSLHVGPWSTCSMPHSRQVRQARRRGKNKEREKDRSKGVKDPEARELIKKKRNRNRQNRQENKYWDIQIGYQTREVMCINKTGKAADLSFCQQEKLPM

UniProtKB · Q9UPZ6

Thrombospondin type-1 domain-containing protein 7A

THS7A_HUMAN · Homo sapiens

View on UniProt ↗

Primary accession: Q9UPZ6
Review status: UniProtKB reviewed (Swiss-Prot)
Gene: THSD7A
Protein existence: 1: Evidence at protein level
Organism: Homo sapiens (Human)
Taxonomy ID: 9606
Alternative names: —
EC number: —
Processing: Precursor
Secondary accessions: —

Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

Biological process

AngiogenesisDifferentiation

Cellular component

Cell membraneCell projectionMembraneSecreted

Domain

Coiled coilRepeatSignalTransmembraneTransmembrane helix

PTM

Disulfide bondGlycoprotein

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