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PMEPA1 Rabbit pAb (APR23153N)

CAT: 0882-APR23153N-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:0882-APR23153N-01Size:50 µL
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Background
This gene encodes a transmembrane protein that contains a Smad interacting motif (SIM) . Expression of this gene is induced by androgens and transforming growth factor beta, and the encoded protein suppresses the androgen receptor and transforming growth factor beta signaling pathways though interactions with Smad proteins. Overexpression of this gene may play a role in multiple types of cancer. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
Overview
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality PMEPA1 Rabbit pAb (APR23153N) .
Synonyms
PMEPA1; STAG1; TMEPAI
Gene ID
56937
UniProt
Q969W9
Cellular Locus
Early endosome membrane, Golgi apparatus membrane, Single-pass membrane protein
Dilution
WB 1:500 - 1:2000 IHC 1:50 - 1:200 IF 1:50 - 1:200
Form
Liquid
Buffer
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Molecular Weight
Calculated MW: 26kDa/27kDa/31kDa Observed MW: Refer to figures
Storage Conditions
Store at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
Gene ID URL
https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=56937
Uniprot URL
https://www.uniprot.org/uniprot/Q969W9
AA Sequence
PSSNSGISATCYGSGGRMEGPPPTYSEVIGHYPGSSFQHQQSSGPPSLLEGTRLHHTHIAPLESAAIWSKEKDKQKGHPL

UniProtKB · Q969W9

Protein TMEPAI

PMEPA_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
Q969W9
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
PMEPA1
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
—
Processing
—
Secondary accessions
Q5TDR6, Q8NER4, Q96B72, Q9UJD3
Protein keywords

Coding sequence diversity

Alternative splicing

Cellular component

EndosomeGolgi apparatusMembrane

Technical term

Proteomics identificationReference proteome

Domain

RepeatTransmembraneTransmembrane helix

Molecular function

Signal transduction inhibitor

Biological process

Ubl conjugation pathway