SUN2 Rabbit pAb (APR22909N)

CAT: 0882-APR22909N-01Size: 50 µLDry Ice: NoHazardous: No

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CAT#:0882-APR22909N-01Size:50 µL

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24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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Background

SUN1 (MIM 607723) and SUN2 are inner nuclear membrane (INM) proteins that play a major role in nuclear-cytoplasmic connection by formation of a 'bridge' across the nuclear envelope, known as the LINC complex, via interaction with the conserved luminal KASH domain of nesprins (e.g., SYNE1; MIM 608441) located in the outer nuclear membrane (ONM) . The LINC complex provides a direct connection between the nuclear lamina and the cytoskeleton, which contributes to nuclear positioning and cellular rigidity (summary by Haque et al., 2010 [PubMed 19933576]) .

Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality SUN2 Rabbit pAb (APR22909N) .

Synonyms

SUN2; UNC84B

Gene ID

25777

UniProt

Q9UH99

Dilution

WB 1:500 - 1:2000 IHC 1:50 - 1:200 IF 1:50 - 1:200

Form

Liquid

Buffer

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Molecular Weight

Calculated MW: 79kDa/80kDa/82kDa Observed MW: 80kDa

Storage Conditions

Store at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Gene ID URL

https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=25777

Uniprot URL

https://www.uniprot.org/uniprot/Q9UH99

AA Sequence

Email for sequence

UniProtKB · Q9UH99

SUN domain-containing protein 2

SUN2_HUMAN · Homo sapiens

View on UniProt ↗

Primary accession: Q9UH99
Review status: UniProtKB reviewed (Swiss-Prot)
Gene: SUN2
Protein existence: 1: Evidence at protein level
Organism: Homo sapiens (Human)
Taxonomy ID: 9606
Alternative names: —
EC number: —
Processing: —
Secondary accessions: B0QY62, O75156, Q2NKN8, Q2T9F7, Q504T5, Q6B4H1, Q7Z3E3

Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

Coding sequence diversity

Alternative splicing

Domain

Coiled coilSignal-anchorTransmembraneTransmembrane helix

PTM

Disulfide bondGlycoproteinPhosphoprotein

Cellular component

EndosomeMembraneNucleus

Biological process

Meiosis

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Alternative Products

Catalog	Name
A16325-01	SUN2 Rabbit pAb
A19782-01	SUN2 Rabbit mAb