CBX2 Rabbit pAb (APR24909N)

CAT: 0882-APR24909N-01Size: 50 µLDry Ice: NoHazardous: No

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CAT#:0882-APR24909N-01Size:50 µL

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24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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Background

This gene encodes a component of the polycomb multiprotein complex, which is required to maintain the transcriptionally repressive state of many genes throughout development via chromatin remodeling and modification of histones. Disruption of this gene in mice results in male-to-female gonadal sex reversal. Mutations in this gene are also associated with gonadal dysgenesis in humans. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene.

Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality CBX2 Rabbit pAb (APR24909N) .

Synonyms

CBX2; CDCA6; M33; SRXY5

Gene ID

84733

UniProt

Q14781

Cellular Locus

Nucleus

Dilution

WB 1:500 - 1:2000

Form

Liquid

Buffer

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Molecular Weight

Calculated MW: 23kDa/56kDa Observed MW: 65kDa

Storage Conditions

Store at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Gene ID URL

https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=84733

Uniprot URL

https://www.uniprot.org/uniprot/Q14781

AA Sequence

EHEKEVQNRKRGKRPRGRPRKLTAMSSCSRRSKLKVGGCAGYADPTSQHPLGVGGRQREGLGPSGRGWHFCQQSVPLLGKQEPPFFLSLSFCCQGPQPAESSSPPLPGASCFSLSCTPLCWVAGSNCCRQALFPPRGSLGDGKEQEACVQ

UniProtKB · Q14781

Chromobox protein homolog 2

CBX2_HUMAN · Homo sapiens

View on UniProt ↗

Primary accession: Q14781
Review status: UniProtKB reviewed (Swiss-Prot)
Gene: CBX2
Protein existence: 1: Evidence at protein level
Organism: Homo sapiens (Human)
Taxonomy ID: 9606
Alternative names: —
EC number: —
Processing: —
Secondary accessions: Q0VDA5, Q9BTB1

Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

Coding sequence diversity

Alternative splicing

Molecular function

Chromatin regulatorDNA-bindingRepressor

Cellular component

ChromosomeNucleus

Biological process

DifferentiationSexual differentiationTranscriptionTranscription regulation

Disease

Disease variant

PTM

Isopeptide bondMethylationPhosphoproteinUbl conjugation

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