SLC8A2 Rabbit pAb (APR22296N)

CAT: 0882-APR22296N-01Size: 50 µLDry Ice: NoHazardous: No

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CAT#:0882-APR22296N-01Size:50 µL

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24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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Background

Mediates the electrogenic exchange of Ca (2+ against Na (+ ions across the cell membrane, and thereby contributes to the regulation of cytoplasmic Ca (2+ levels and Ca (2+-dependent cellular processes. Contributes to cellular Ca (2+ homeostasis in excitable cells. Contributes to the rapid decrease of cytoplasmic Ca (2+ levels back to baseline after neuronal activation, and thereby contributes to modulate synaptic plasticity, learning and memory. Plays a role in regulating urinary Ca (2+ and Na (+ excretion.

Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality SLC8A2 Rabbit pAb (APR22296N) .

Synonyms

SLC8A2; NCX2

Gene ID

6543

UniProt

Q9UPR5

Cellular Locus

Basolateral cell membrane, Cell membrane, Cell projection, Multi-pass membrane protein, Perikaryon, dendrite, dendritic spine

Dilution

WB 1:500 - 1:2000

Form

Liquid

Buffer

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Molecular Weight

Calculated MW: 100kDa Observed MW: 100kDa

Storage Conditions

Store at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Gene ID URL

https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=6543

Uniprot URL

https://www.uniprot.org/uniprot/Q9UPR5

AA Sequence

LMTGAGNVLRRHAADASRRAAPAEGAGEDEDDGASRIFFEPSLYHCLENCGSVLLSVTCQGGEGNSTFYVDYRTEDGSAKAGSDYEYSEGT

UniProtKB · Q9UPR5

Sodium/calcium exchanger 2

NAC2_HUMAN · Homo sapiens

View on UniProt ↗

Primary accession: Q9UPR5
Review status: UniProtKB reviewed (Swiss-Prot)
Gene: SLC8A2
Protein existence: 1: Evidence at protein level
Organism: Homo sapiens (Human)
Taxonomy ID: 9606
Alternative names: —
EC number: —
Processing: Precursor
Secondary accessions: B4DYQ9

Protein keywords

Biological process

AntiportCalcium transportIon transportSodium transportTransport

Ligand

CalciumMetal-bindingSodium

Molecular function

Calmodulin-binding

Cellular component

Cell membraneCell projectionMembraneSynapse

PTM

GlycoproteinPhosphoprotein

Technical term

Proteomics identificationReference proteome

Domain

RepeatSignalTransmembraneTransmembrane helix

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