ENOS Rabbit pAb (APR22044N)

CAT: 0882-APR22044N-01Size: 50 µLDry Ice: NoHazardous: No

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CAT#:0882-APR22044N-01Size:50 µL

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24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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Background

Nitric oxide is a reactive free radical which acts as a biologic mediator in several processes, including neurotransmission and antimicrobial and antitumoral activities. Nitric oxide is synthesized from L-arginine by nitric oxide synthases. Variations in this gene are associated with susceptibility to coronary spasm. Alternative splicing and the use of alternative promoters results in multiple transcript variants.

Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality eNOS Rabbit pAb (APR22044N) .

Synonyms

NOS3; ECNOS; eNOS

Gene ID

4846

UniProt

P29474

Cellular Locus

Cell membrane, Cytoplasm, Golgi apparatus, Membrane, caveola, cytoskeleton

Applications

WB (Rattus norvegicus, Mus musculus, Homo sapiens) IF (Homo sapiens, Rattus norvegicus) IHC (Homo sapiens)

Dilution

WB 1:500 - 1:2000 IF 1:50 - 1:200

Form

Liquid

Buffer

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Molecular Weight

Calculated MW: 67kDa/68kDa/133kDa Observed MW: 140KDa

Storage Conditions

Store at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Gene ID URL

https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=4846

Uniprot URL

https://www.uniprot.org/uniprot/P29474

AA Sequence

MGNLKSVAQEPGPPCGLGLGLGLGLCGKQGPATPAPEPSRAPASLLPPAPEHSPPSSPLTQPPEGPKFPRVKNWEVGSITYDTLSAQAQQDGPCTPRRCLGSLVFPRKLQGRPSPGPPAP

UniProtKB · P29474

Nitric oxide synthase 3

NOS3_HUMAN · Homo sapiens

View on UniProt ↗

Primary accession: P29474
Review status: UniProtKB reviewed (Swiss-Prot)
Gene: NOS3
Protein existence: 1: Evidence at protein level
Organism: Homo sapiens (Human)
Taxonomy ID: 9606
Alternative names: —
EC number: 1.14.13.39
Processing: —
Secondary accessions: A0S0A7, A0S0A8, A8KA63, B2RCQ1, E9PFR2, Q13662, Q14251, Q14434, Q548C1, Q6GSL5, Q9UDC6

Protein keywords

Technical term

3D-structureDirect protein sequencingProteomics identificationReference proteome

Coding sequence diversity

Alternative splicing

Ligand

CalciumFADFlavoproteinFMNHemeIronMetal-bindingNADPZinc

Molecular function

Calmodulin-bindingOxidoreductase

Cellular component

Cell membraneCytoplasmCytoskeletonGolgi apparatusMembrane

PTM

LipoproteinMyristatePalmitatePhosphoprotein

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MBS8597246-01	eNOS Rabbit pAb
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