CTRB1 Rabbit pAb (APR21590N)

CAT: 0882-APR21590N-01Size: 50 µLDry Ice: NoHazardous: No

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CAT#:0882-APR21590N-01Size:50 µL

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Background

This gene encodes a member of the serine protease family of enzymes and forms a principal precursor of the pancreatic proteolytic enzymes. The encoded preproprotein is synthesized in the acinar cells of the pancreas and secreted into the small intestine where it undergoes proteolytic activation to generate a functional enzyme. This gene is located adjacent to a related chymotrypsinogen gene. This gene encodes distinct isoforms, some or all of which may undergo similar processing to generate the mature protein.

Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality CTRB1 Rabbit pAb (APR21590N) .

Synonyms

CTRB1; CTRB

Gene ID

1504

UniProt

P17538

Cellular Locus

Secreted, extracellular space

Dilution

WB 1:500 - 1:2000 IHC 1:50 - 1:100 IF 1:50 - 1:100

Form

Liquid

Buffer

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Molecular Weight

Calculated MW: 27kDa Observed MW: 28kDa

Storage Conditions

Store at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Gene ID URL

https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=1504

Uniprot URL

https://www.uniprot.org/uniprot/P17538

AA Sequence

RTSDVVVAGEFDQGSDEENIQVLKIAKVFKNPKFSILTVNNDITLLKLATPARFSQTVSAVCLPSADDDFPAGTLCATTGWGKTKYNANKTPDKLQQAALPLLSNAECKKSWGRRITDVMICAGASGVSSCMGDSGGPLVCQKDGAWTLVGIVSWGSDTCSTSSPGVYARVTKLIPWVQKILAAN

UniProtKB · P17538

Chymotrypsinogen B

CTRB1_HUMAN · Homo sapiens

View on UniProt ↗

Primary accession: P17538
Review status: UniProtKB reviewed (Swiss-Prot)
Gene: CTRB1
Protein existence: 1: Evidence at protein level
Organism: Homo sapiens (Human)
Taxonomy ID: 9606
Alternative names: —
EC number: 3.4.21.1
Processing: Precursor
Secondary accessions: —

Protein keywords

Biological process

Digestion

PTM

Disulfide bondPhosphoproteinZymogen

Molecular function

HydrolaseProteaseSerine protease

Technical term

Proteomics identificationReference proteome

Cellular component

Secreted

Domain

Signal

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