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JAM2 Rabbit pAb (APR20697N)

CAT: 0882-APR20697N-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:0882-APR20697N-01Size:50 µL
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Background
This gene belongs to the immunoglobulin superfamily, and the junctional adhesion molecule (JAM) family. The protein encoded by this gene is a type I membrane protein that is localized at the tight junctions of both epithelial and endothelial cells. It acts as an adhesive ligand for interacting with a variety of immune cell types, and may play a role in lymphocyte homing to secondary lymphoid organs. Alternatively spliced transcript variants have been found for this gene.
Overview
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality JAM2 Rabbit pAb (APR20697N) .
Synonyms
JAM2; C21orf43; CD322; JAM-B; JAMB; PRO245; VE-JAM; VEJAM
Gene ID
58494
UniProt
P57087
Cellular Locus
Cell junction, Cell membrane, Single-pass type I membrane protein, tight junction
Dilution
WB 1:500 - 1:2000
Form
Liquid
Buffer
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Molecular Weight
Calculated MW: 29kDa/33kDa/34kDa Observed MW: 45kDa
Storage Conditions
Store at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
Gene ID URL
https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=58494
Uniprot URL
https://www.uniprot.org/uniprot/P57087
AA Sequence
FSAPKDQQVVTAVEYQEAILACKTPKKTVSSRLEWKKLGRSVSFVYYQQTLQGDFKNRAEMIDFNIRIKNVTRSDAGKYRCEVSAPSEQGQNLEEDTVTLEVLVAPAVPSCEVPSSALSGTVVELRCQDKEGNPAPEYTWFKDGIRLLENPRLGSQSTNSSYTMNTKTGTLQFNTVSKLDTGEYSCEARNSVGYRRCPGKRMQVDDLNIS

UniProtKB · P57087

Junctional adhesion molecule B

JAM2_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
P57087
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
JAM2
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
JAM-B
EC number
—
Processing
Precursor
Secondary accessions
B2R6T9, B4DGT9, Q6UXG6, Q6YNC1
Protein keywords

Coding sequence diversity

Alternative splicing

Cellular component

Cell junctionCell membraneMembraneTight junction

Technical term

Direct protein sequencingProteomics identificationReference proteome

Disease

Disease variant

PTM

Disulfide bondGlycoprotein

Domain

Immunoglobulin domainSignalTransmembraneTransmembrane helix