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SCG2 Rabbit pAb (APR20148N)

CAT: 0882-APR20148N-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:0882-APR20148N-01Size:50 µL
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Background
The protein encoded by this gene is a member of the chromogranin/secretogranin family of neuroendocrine secretory proteins. Studies in rodents suggest that the full-length protein, secretogranin II, is involved in the packaging or sorting of peptide hormones and neuropeptides into secretory vesicles. The full-length protein is cleaved to produce the active peptide secretoneurin, which exerts chemotaxic effects on specific cell types, and EM66, whose function is unknown.
Overview
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality SCG2 Rabbit pAb (APR20148N) .
Synonyms
SCG2; CHGC; EM66; SN; SgII
Gene ID
7857
UniProt
P13521
Cellular Locus
Secreted
Dilution
WB 1:500 - 1:2000
Form
Liquid
Buffer
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Molecular Weight
Calculated MW: 70kDa Observed MW: 71kDa
Storage Conditions
Store at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
Gene ID URL
https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=7857
Uniprot URL
https://www.uniprot.org/uniprot/P13521
AA Sequence
EALPDGLSVEDILNLLGMESAANQKTSYFPNPYNQEKVLPRLPYGAGRSRSNQLPKAAWIPHVENRQMAYENLNDKDQELGEYLARMLVKYPEIINSNQVKRVPGQGSSEDDLQEEEQIEQAIKEHLNQGSSQETDKLAPVSKRFPVGPPKNDDTPNRQYWDEDLLMKVLEYLNQEKAEKGREHIAKRAMENM

UniProtKB · P13521

Secretogranin-2

SCG2_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
P13521
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
SCG2
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
—
Processing
Precursor
Secondary accessions
B2R662, Q53T11, Q8TBH3
Protein keywords

Ligand

Calcium

PTM

Cleavage on pair of basic residuesGlycoproteinPhosphoproteinSulfation

Technical term

Proteomics identificationReference proteome

Cellular component

Secreted

Domain

Signal