MDH2 Rabbit pAb (APR20105N)

CAT: 0882-APR20105N-01Size: 50 µLDry Ice: NoHazardous: No

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CAT#:0882-APR20105N-01Size:50 µL

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24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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Background

Malate dehydrogenase catalyzes the reversible oxidation of malate to oxaloacetate, utilizing the NAD/NADH cofactor system in the citric acid cycle. The protein encoded by this gene is localized to the mitochondria and may play pivotal roles in the malate-aspartate shuttle that operates in the metabolic coordination between cytosol and mitochondria. Several transcript variants encoding different isoforms have been found for this gene.

Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality MDH2 Rabbit pAb (APR20105N) .

Synonyms

MDH2; EIEE51; M-MDH; MDH; MGC:3559; MOR1

Gene ID

4191

UniProt

P40926

Cellular Locus

Mitochondrion matrix

Dilution

WB 1:500 - 1:2000 IF 1:50 - 1:200

Form

Liquid

Buffer

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Molecular Weight

Calculated MW: 30kDa/35kDa Observed MW: 35kDa

Storage Conditions

Store at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Gene ID URL

https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=4191

Uniprot URL

https://www.uniprot.org/uniprot/P40926

AA Sequence

AHTPGVAADLSHIETKAAVKGYLGPEQLPDCLKGCDVVVIPAGVPRKPGMTRDDLFNTNATIVATLTAACAQHCPEAMICVIANPVNSTIPITAEVFKKHGVYNPNKIFGVTTLDIVRANTFVAELKGLDPARVNVPVIGGHAGKTIIPLISQCTPKVDFPQDQLTALTGRIQEAGTEVVKAKAGAGSATLSMAYAGARFVFSLVDAMNGKEGVVECSFVKSQETECTYFSTPLLLGKKGIEKNLGIGKVSSFEEKMISDAIPELKASIKKGEDFVKTLK

UniProtKB · P40926

Malate dehydrogenase, mitochondrial

MDHM_HUMAN · Homo sapiens

View on UniProt ↗

Primary accession: P40926
Review status: UniProtKB reviewed (Swiss-Prot)
Gene: MDH2
Protein existence: 1: Evidence at protein level
Organism: Homo sapiens (Human)
Taxonomy ID: 9606
Alternative names: —
EC number: 1.1.1.37
Processing: Precursor
Secondary accessions: A8K414, B2RE78, B4DE44, E9PDB2, O43682

Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

PTM

AcetylationGlycoproteinLipoproteinPalmitatePhosphoprotein

Coding sequence diversity

Alternative splicing

Disease

Disease variantEpilepsy

Cellular component

Mitochondrion

Ligand

NAD

Molecular function

Oxidoreductase

Domain

Transit peptide

Biological process

Tricarboxylic acid cycle

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