A1CF Rabbit pAb (APR19683N)

CAT: 0882-APR19683N-01Size: 50 µLDry Ice: NoHazardous: No

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CAT#:0882-APR19683N-01Size:50 µL

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24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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Background

Mammalian apolipoprotein B mRNA undergoes site-specific C to U deamination, which is mediated by a multi-component enzyme complex containing a minimal core composed of APOBEC-1 and a complementation factor encoded by this gene. The gene product has three non-identical RNA recognition motifs and belongs to the hnRNP R family of RNA-binding proteins. It has been proposed that this complementation factor functions as an RNA-binding subunit and docks APOBEC-1 to deaminate the upstream cytidine. Studies suggest that the protein may also be involved in other RNA editing or RNA processing events. Several transcript variants encoding a few different isoforms have been found for this gene.

Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality A1CF Rabbit pAb (APR19683N) .

Synonyms

A1CF; ACF; ACF64; ACF65; APOBEC1CF; ASP

Gene ID

29974

UniProt

Q9NQ94

Cellular Locus

Cytoplasm, Endoplasmic reticulum, Nucleus

Dilution

WB 1:500 - 1:2000 IHC 1:50 - 1:200

Form

Liquid

Buffer

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Molecular Weight

Calculated MW: 55kDa/58kDa/62kDa/64kDa/65kDa Observed MW: 65kDa

Storage Conditions

Store at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Gene ID URL

https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=29974

Uniprot URL

https://www.uniprot.org/uniprot/Q9NQ94

AA Sequence

APPERGCEIFIGKLPRDLFEDELIPLCEKIGKIYEMRMMMDFNGNNRGYAFVTFSNKVEAKNAIKQLNNYE

UniProtKB · Q9NQ94

APOBEC1 complementation factor

A1CF_HUMAN · Homo sapiens

View on UniProt ↗

Primary accession: Q9NQ94
Review status: UniProtKB reviewed (Swiss-Prot)
Gene: A1CF
Protein existence: 1: Evidence at protein level
Organism: Homo sapiens (Human)
Taxonomy ID: 9606
Alternative names: —
EC number: —
Processing: —
Secondary accessions: A1L4F2, A8K7G7, B7ZM14, Q5SZQ0, Q9NQ93, Q9NQX8, Q9NQX9, Q9NXC9, Q9NZD3

Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

Coding sequence diversity

Alternative splicing

Cellular component

CytoplasmEndoplasmic reticulumNucleus

Biological process

mRNA processing

PTM

Phosphoprotein

Domain

Repeat

Molecular function

RNA-binding

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APR19643N-01	SPTB Rabbit pAb (APR19643N)
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APR19883N-01	CST1 Rabbit pAb (APR19883N)
APR19687N-01	AADAT Rabbit pAb (APR19687N)

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