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PRIM2 Rabbit pAb (APR18546N)

CAT: 0882-APR18546N-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:0882-APR18546N-01Size:50 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
This gene encodes the 58 kilodalton subunit of DNA primase, an enzyme that plays a key role in the replication of DNA. The encoded protein forms a heterodimer with a 49 kilodalton subunit. This heterodimer functions as a DNA-directed RNA polymerase to synthesize small RNA primers that are used to create Okazaki fragments on the lagging strand of the DNA. Alternative splicing of this gene results in multiple transcript variants. This gene has a related pseudogene, which is also present on chromosome 6.
Overview
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality PRIM2 Rabbit pAb (APR18543N3) .
Synonyms
PRIM2; PRIM2A; p58
Gene ID
5558
UniProt
P49643
Dilution
WB 1:500 - 1:2000
Form
Liquid
Buffer
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Molecular Weight
Calculated MW: 19kDa/58kDa Observed MW: 59kDa
Storage Conditions
Store at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
Gene ID URL
https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=5558
Uniprot URL
https://www.uniprot.org/uniprot/P49643
AA Sequence
MEFSGRKWRKLRLAGDQRNASYPHCLQFYLQPPSENISLIEFENLAIDRVKLLKSVENLGVSYVKGTEQYQSKLESELRKLKFSYRENLEDEYEPRRRDHISHFILRLAYCQSEELRRWFIQQEMDLLRFRFSILPKDKIQDFLKDSQLQFEAISDEEKTLREQEIVASS

UniProtKB · P49643

DNA primase large subunit

PRI2_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
P49643
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
PRIM2
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
—
Processing
—
Secondary accessions
Q53FJ8, Q6P1Q7, Q8WVL2, Q9H413
Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

Ligand

4Fe-4SIronIron-sulfurMetal-binding

Coding sequence diversity

Alternative splicing

Biological process

DNA replication

Molecular function

DNA-binding

PTM

Phosphoprotein

Cellular component

Primosome

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