YAP1 Rabbit pAb (APR17643N)

CAT: 0882-APR17643N-01Size: 50 µLDry Ice: NoHazardous: No

1 / 1

CAT#:0882-APR17643N-01Size:50 µL

Selected

24/48H Stock Items & 2 to 6 Weeks non Stock Items.

Quick Request Actions

Background

This gene encodes a downstream nuclear effector of the Hippo signaling pathway which is involved in development, growth, repair, and homeostasis. This gene is known to play a role in the development and progression of multiple cancers as a transcriptional regulator of this signaling pathway and may function as a potential target for cancer treatment. Alternative splicing results in multiple transcript variants encoding different isoforms.

Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality YAP1 Rabbit pAb (APR17643N) .

Synonyms

COB1; YAP; YAP2; YAP65; YKI; YAP1

Gene ID

10413

UniProt

P46937

Cellular Locus

Cytoplasm, Nucleus

Applications

WB (Homo sapiens, Mus musculus) IHC (Homo sapiens) IF (Mus musculus)

Dilution

WB 1:500 - 1:2000 IHC 1:50 - 1:100 IF 1:50 - 1:200

Form

Liquid

Buffer

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Molecular Weight

Calculated MW: 36kDa/48kDa/49kDa/50kDa/52kDa/53kDa/54kDa Observed MW: 72kDa

Storage Conditions

Store at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Gene ID URL

https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=10413

Uniprot URL

https://www.uniprot.org/uniprot/P46937

AA Sequence

PTAQHLRQSSFEIPDDVPLPAGWEMAKTSSGQRYFLNHIDQTTTWQDPRKAMLSQMNVTAPTSPPVQQNMMNSASGPLPDGWEQAMTQDGEIYYINHKNKTTSWLDPRLDPRFAMNQRISQSAPVKQPPPLAPQSPQGGVMGGSNSNQQQQMRLQQLQMEKERLRLKQQELLRQAMRNINPSTANSPKCQELALRSQLPTLEQDGGTQNPVSSPGMSQELRTMTTNSSDPFLNSGTYHSRDESTDSGLSMSSYSVPRTPDDFLNSVDEMDTGDTINQSTLPSQQNRFPDYLEAIPGTNVDLGTLEGDGMNIEGEELMPSLQEALSSDILNDMESVLAATKLDKESFLTWL

UniProtKB · P46937

Transcriptional coactivator YAP1

YAP1_HUMAN · Homo sapiens

View on UniProt ↗

Primary accession: P46937
Review status: UniProtKB reviewed (Swiss-Prot)
Gene: YAP1
Protein existence: 1: Evidence at protein level
Organism: Homo sapiens (Human)
Taxonomy ID: 9606
Alternative names: Yes-associated protein 1
EC number: —
Processing: —
Secondary accessions: B4DTY1, B7ZA01, E3WEB5, E3WEB6, E9PRV2, F5H202, K0KQ18, K0KYZ8, K0L195, K0L1G3, Q7Z574, Q8IUY9

Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

Molecular function

ActivatorRepressor

Coding sequence diversity

Alternative splicing

Cellular component

Cell junctionCell membraneCytoplasmMembraneNucleusTight junction

Domain

Coiled coilRepeat

PTM

PhosphoproteinUbl conjugation

Disease

Proto-oncogene

Biological process

TranscriptionTranscription regulation

Related Products

Catalog	Name
APR23509N-01	YAP1 Rabbit pAb (APR23509N)
APR18394N-01	YAP1 Rabbit pAb (APR18394N)
APR18454N-01	YAP1 Rabbit pAb (APR18454N)
APR18671N-01	YAP1 Rabbit pAb (APR18671N)
APR29292N-01	MonoMethyl-YAP1-K342 Rabbit pAb (APR29292N)
AMR00938N-01	Phospho-YAP1-S127 Rabbit pAb (AMR00938N)
APR29227N-01	Phospho-YAP1-S128 Rabbit pAb (APR29227N)
APR18393N-01	[KO Validated] YAP1 Rabbit pAb (APR18393N)
AMR01191N-01	Phospho-YAP1-S397 Rabbit pAb (AMR01191N)
APR29673N-01	Non-phospho-YAP1-S127 Rabbit pAb (APR29673N)

Alternative Products

Catalog	Name
GTR17692318	Phospho-YAP1/YAP1 Rabbit Monoclonal Antibody
HY-P80374-01	YAP1 Antibody (Rabbit)
MBS8603627-01	YAP1 Rabbit mAb
MBS8548601-01	YAP1 Rabbit pAb