MSH2 Rabbit pAb (APR17290N)

• Background:

  This locus is frequently mutated in hereditary nonpolyposis colon cancer (HNPCC) . When cloned, it was discovered to be a human homolog of the E. coli mismatch repair gene mutS, consistent with the characteristic alterations in microsatellite sequences (RER+ phenotype) found in HNPCC. Two transcript variants encoding different isoforms have been found for this gene.

• Synonyms:

  MSH2; COCA1; FCC1; HNPCC; HNPCC1; LCFS2

• Gene ID:

  4436

• UniProt:

  P43246

• Cellular Locus:

  Nucleus

• Dilution:

  WB 1:500 - 1:1000 IF 1:20 - 1:50

• Form:

  Liquid

• Buffer:

  Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

• Molecular Weight:

  Calculated MW: 97kDa/104kDa Observed MW: 150kDa

• Storage Conditions:

  Store at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

• Overview:

  We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality MSH2 Rabbit pAb (APR17290N) .

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=4436

• Uniprot URL:

  https://www.uniprot.org/uniprot/P43246

• AA Sequence:

  Email for sequence