[KO Validated] Smad3 Rabbit mAb (AMR13091N)

• Background:

  The protein encoded by this gene belongs to the SMAD, a family of proteins similar to the gene products of the Drosophila gene 'mothers against decapentaplegic' (Mad) and the C. elegans gene Sma. SMAD proteins are signal transducers and transcriptional modulators that mediate multiple signaling pathways. This protein functions as a transcriptional modulator activated by transforming growth factor-beta and is thought to play a role in the regulation of carcinogenesis. [provided by RefSeq, Apr 2009]

• Synonyms:

  HSPC193; HsT17436; JV15-2; LDS1C; LDS3; MADH3; SMAD3

• Gene ID:

  4088

• UniProt:

  P84022

• Cellular Locus:

  Cytoplasm, Nucleus

• Applications:

  WB (Mus musculus)

• Dilution:

  WB 1:500 - 1:2000 IHC 1:50 - 1:200 IF 1:50 - 1:200 IP 1:50 - 1:200

• Form:

  Liquid

• Buffer:

  Buffer: PBS with 0.02% sodium azide, 0.05% BSA, 50% glycerol, pH7.3.

• Molecular Weight:

  Calculated MW: 48kDa Observed MW: 52kDa

• Storage Conditions:

  Store at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

• Overview:

  We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality [KO Validated] Smad3 Rabbit mAb (APR24454N5) .

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=4088

• Uniprot URL:

  https://www.uniprot.org/uniprot/P84022

• AA Sequence:

  Email for sequence