EIF2A Rabbit mAb (AMR11840N)

CAT: 0882-AMR11840N-01Size: 50 µLDry Ice: NoHazardous: No

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CAT#:0882-AMR11840N-01Size:50 µL

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24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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Background

This gene encodes a eukaryotic translation initiation factor that catalyzes the formation of puromycin-sensitive 80 S preinitiation complexes and the poly (U) -directed synthesis of polyphenylalanine at low concentrations of Mg2+. This gene should not be confused with eIF2-alpha (EIF2S1, Gene ID: 1965), the alpha subunit of the eIF2 translation initiation complex. Although both of these proteins function in binding initiator tRNA to the 40 S ribosomal subunit, the encoded protein does so in a codon-dependent manner, whereas eIF2 complex requires GTP. Alternative splicing of this gene results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jan 2016]

Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality eIF2A Rabbit mAb (AMR11840N) .

Synonyms

CDA02; EIF-2A; MST089; MSTP004; MSTP089

Gene ID

83939

UniProt

Q9BY44

Dilution

WB 1:500 - 1:2000 IHC 1:50 - 1:200

Form

Liquid

Buffer

Buffer: PBS with 0.02% sodium azide, 0.05% BSA, 50% glycerol, pH7.3.

Molecular Weight

Calculated MW: 65kDa Observed MW: 60kDa

Storage Conditions

Store at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Gene ID URL

https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=83939

Uniprot URL

https://www.uniprot.org/uniprot/Q9BY44

AA Sequence

Email for sequence

UniProtKB · Q9BY44

Eukaryotic translation initiation factor 2A

EIF2A_HUMAN · Homo sapiens

View on UniProt ↗

Primary accession: Q9BY44
Review status: UniProtKB reviewed (Swiss-Prot)
Gene: EIF2A
Protein existence: 1: Evidence at protein level
Organism: Homo sapiens (Human)
Taxonomy ID: 9606
Alternative names: eIF-2A
EC number: —
Processing: —
Secondary accessions: A8MPS6, B4DF96, B4DQ14, D3DNI9, Q5QTR2, Q7Z4E9, Q8NFM1, Q96EW9, Q96K81

Protein keywords

Technical term

3D-structureDirect protein sequencingProteomics identificationReference proteome

PTM

AcetylationPhosphoprotein

Coding sequence diversity

Alternative splicing

Domain

Coiled coilRepeatWD repeat

Molecular function

Initiation factor

Biological process

Protein biosynthesisTranslation regulation

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