Phospho-IRE1-S724 Rabbit pAb (AMR01157N)

• Background:

  The protein encoded by this gene is the ER to nucleus signalling 1 protein, a human homologue of the yeast Ire1 gene product. This protein possesses intrinsic kinase activity and an endoribonuclease activity and it is important in altering gene expression as a response to endoplasmic reticulum-based stress signals.

• Synonyms:

  ERN1; IRE1; IRE1P; IRE1a; hIRE1p

• Gene ID:

  2081

• UniProt:

  O75460

• Cellular Locus:

  Endoplasmic reticulum membrane, Single-pass type I membrane protein

• Applications:

  WB (Homo sapiens, Mus musculus, Rattus norvegicus, Trachemys scripta elegans)

• Dilution:

  WB 1:500 - 1:2000 IHC 1:50 - 1:200

• Form:

  Liquid

• Buffer:

  Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

• Molecular Weight:

  Calculated MW: 6kDa/109kDa Observed MW: 130KDa

• Storage Conditions:

  Store at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

• Overview:

  We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality Phospho-IRE1-S724 Rabbit pAb (AMR01157N) .

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=2081

• Uniprot URL:

  https://www.uniprot.org/uniprot/O75460

• AA Sequence:

  Email for sequence