OAS2 Mouse Monoclonal Antibody [Clone ID: LBI4B11]

• Background:

  This gene encodes a member of the 2-5A synthetase family, essential proteins involved in the innate immune response to viral infection. The encoded protein is induced by interferons and uses adenosine triphosphate in 2'-specific nucleotidyl transfer reactions to synthesize 2',5'-oligoadenylates (2-5As) . These molecules activate latent RNase L, which results in viral RNA degradation and the inhibition of viral replication. The three known members of this gene family are located in a cluster on chromosome 12. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jul

• Synonyms:

  MGC78578

• Gene Name:

  Homo sapiens 2'-5'-oligoadenylate synthetase 2 (OAS2), transcript variant 2, mRNA.

• Gene ID:

  4939

• UniProt:

  P29728

• Conjugation:

  Unconjugated

• Dilution:

  WB 1:500

• Form:

  Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

• Buffer:

  Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

• Function:

  Druggable Genome

• Storage Conditions:

  Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

• Symbol:

  OAS2

• Overview:

  Carrier-free (BSA/glycerol-free) OAS2 mouse monoclonal antibody, clone LBI4B11

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/?term=4939

• Uniprot URL:

  https://www.uniprot.org/uniprot/P29728