OAS2 Mouse Monoclonal Antibody [Clone ID: LBI6E6]

• Background:

  This gene encodes a member of the 2-5A synthetase family, essential proteins involved in the innate immune response to viral infection. The encoded protein is induced by interferons and uses adenosine triphosphate in 2'-specific nucleotidyl transfer reactions to synthesize 2',5'-oligoadenylates (2-5As) . These molecules activate latent RNase L, which results in viral RNA degradation and the inhibition of viral replication. The three known members of this gene family are located in a cluster on chromosome 12. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jul

• Synonyms:

  MGC78578

• Gene Name:

  2'-5'-oligoadenylate synthetase 2

• Gene ID:

  4939

• UniProt:

  P29728

• Conjugation:

  Unconjugated

• Concentration:

  1 mg/ml

• Dilution:

  WB 1:2000

• Form:

  PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

• Buffer:

  PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

• Function:

  Druggable Genome

• Storage Conditions:

  Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

• Symbol:

  OAS2

• Overview:

  OAS2 mouse monoclonal antibody, clone LBI6E6

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/?term=4939

• Uniprot URL:

  https://www.uniprot.org/uniprot/P29728