Neuraminidase (NEU1) Mouse Monoclonal Antibody [Clone ID: LBI3D4]

• Background:

  The protein encoded by this gene is a lysosomal enzyme that cleaves terminal sialic acid residues from substrates such as glycoproteins and glycolipids. In the lysosome, this enzyme is part of a heterotrimeric complex together with beta-galactosidase and cathepsin A (the latter is also referred to as 'protective protein') . Mutations in this gene can lead to sialidosis, a lysosomal storage disease that can be type 1 (cherry red spot-myoclonus syndrome or normosomatic type), which is late-onset, or type 2 (the dysmorphic type), which occurs at an earlier age with increased severity. [provided by RefSeq, Jul 2008]

• Synonyms:

  NANH; NEU; SIAL1

• Gene Name:

  Homo sapiens neuraminidase 1 (NEU1), mRNA.

• Gene ID:

  4758

• UniProt:

  Q99519

• Conjugation:

  Unconjugated

• Related Pathways:

  Lysosome, Other glycan degradation, Sphingolipid metabolism

• Field of Research:

  Lysosome, Other glycan degradation, Sphingolipid metabolism

• Dilution:

  WB 1:2000, IHC 1:150

• Form:

  Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

• Buffer:

  Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

• Function:

  Druggable Genome, Transmembrane

• Storage Conditions:

  Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

• Symbol:

  NEU1

• Overview:

  Carrier-free (BSA/glycerol-free) NEU1 mouse monoclonal antibody, clone LBI3D4

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/?term=4758

• Uniprot URL:

  https://www.uniprot.org/uniprot/Q99519