NM23A (NME1) Mouse Monoclonal Antibody [Clone ID: LBI4G3]

• Background:

  This gene (NME1) was identified because of its reduced mRNA transcript levels in highly metastatic cells. Nucleoside diphosphate kinase (NDK) exists as a hexamer composed of 'A' (encoded by this gene) and 'B' (encoded by NME2) isoforms. Mutations in this gene have been identified in aggressive neuroblastomas. Two transcript variants encoding different isoforms have been found for this gene. Co-transcription of this gene and the neighboring downstream gene (NME2) generates naturally-occurring transcripts (NME1-NME2), which encodes a fusion protein comprised of sequence sharing identity with each individual gene product. [provided by RefSeq, Jul 2008]

• Synonyms:

  AWD; GAAD; NB; NBS; NDKA; NDPK-A; NDPKA; NM23; NM23-H1

• Gene Name:

  Homo sapiens NME/NM23 nucleoside diphosphate kinase 1 (NME1), transcript variant 1, mRNA.

• Gene ID:

  4830

• UniProt:

  P15531

• Conjugation:

  Unconjugated

• Related Pathways:

  Metabolic pathways, Purine metabolism, Pyrimidine metabolism

• Field of Research:

  Metabolic pathways, Purine metabolism, Pyrimidine metabolism

• Dilution:

  WB 1:2000, IHC 1:150

• Form:

  Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

• Buffer:

  Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

• Function:

  Druggable Genome, Stem cell - Pluripotency

• Storage Conditions:

  Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

• Symbol:

  NME1

• Overview:

  Carrier-free (BSA/glycerol-free) NME1 mouse monoclonal antibody, clone LBI4G3

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/?term=4830

• Uniprot URL:

  https://www.uniprot.org/uniprot/P15531