CIAP2 (BIRC3) Mouse Monoclonal Antibody [Clone ID: LBI2G7]

• Background:

  The protein encoded by this gene is a member of a family of proteins that inhibits apoptosis by binding to tumor necrosis factor receptor-associated factors TRAF1 and TRAF2, probably by interfering with activation of ICE-like proteases. The encoded protein inhibits apoptosis induced by serum deprivation but does not affect apoptosis resulting from exposure to menadione, a potent inducer of free radicals. The amino acid sequence predicts three baculovirus IAP repeat domains and a ring finger domain. Transcript variants encoding the same isoform have been identified. [provided by RefSeq]

• Synonyms:

  AIP1; API2; c-IAP2; CIAP2; HAIP1; HIAP1; MALT2; MIHC; RNF49

• Gene Name:

  Homo sapiens baculoviral IAP repeat containing 3 (BIRC3), transcript variant 1, mRNA.

• Gene ID:

  330

• UniProt:

  Q13489

• Conjugation:

  Unconjugated

• Related Pathways:

  Apoptosis, Focal adhesion, NOD-like receptor signaling pathway, Pathways in cancer, Small cell lung cancer, Ubiquitin mediated proteolysis

• Field of Research:

  Apoptosis, Focal adhesion, NOD-like receptor signaling pathway, Pathways in cancer, Small cell lung cancer, Ubiquitin mediated proteolysis

• Dilution:

  WB 1:2000

• Form:

  Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

• Buffer:

  Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

• Function:

  Druggable Genome

• Storage Conditions:

  Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

• Symbol:

  BIRC3

• Overview:

  Carrier-free (BSA/glycerol-free) BIRC3 mouse monoclonal antibody, clone LBI2G7

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/?term=330

• Uniprot URL:

  https://www.uniprot.org/uniprot/Q13489