PDE6 gamma (PDE6G) Mouse Monoclonal Antibody [Clone ID: LBI2F5]

• Background:

  This gene encodes the gamma subunit of cyclic GMP-phosphodiesterase, which is composed of alpha- and beta- catalytic subunits and two identical, inhibitory gamma subunits. This gene is expressed in rod photoreceptors and functions in the phototransduction signaling cascade. It is also expressed in a variety of other tissues, and has been shown to regulate the c-Src protein kinase and G-protein-coupled receptor kinase 2. Alternative splicing results in multiple transcript variants. [provided by RefSeq]

• Synonyms:

  PDEG; RP57

• Gene Name:

  Homo sapiens phosphodiesterase 6G (PDE6G), transcript variant 1, mRNA.

• Gene ID:

  5148

• UniProt:

  P18545

• Conjugation:

  Unconjugated

• Related Pathways:

  Progesterone-mediated oocyte maturation, Purine metabolism

• Field of Research:

  Progesterone-mediated oocyte maturation, Purine metabolism

• Dilution:

  WB 1:2000, IHC 1:150

• Form:

  Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

• Buffer:

  Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

• Function:

  Druggable Genome

• Storage Conditions:

  Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

• Symbol:

  PDE6G

• Overview:

  Carrier-free (BSA/glycerol-free) PDE6G mouse monoclonal antibody, clone LBI2F5

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/?term=5148

• Uniprot URL:

  https://www.uniprot.org/uniprot/P18545