ERAB (HSD17B10) Mouse Monoclonal Antibody [Clone ID: LBI10B4]

• Background:

  This gene encodes 3-hydroxyacyl-CoA dehydrogenase type II, a member of the short-chain dehydrogenase/reductase superfamily. The gene product is a mitochondrial protein that catalyzes the oxidation of a wide variety of fatty acids, alcohols, and steroids. The protein has been implicated in the development of Alzheimer's disease, and mutations in the gene are the cause of 2-methyl-3-hydroxybutyryl-CoA dehydrogenase deficiency (MHBD) . Several alternatively spliced transcript variants have been identified, but the full-length nature of only two transcript variants has been determined.

• Synonyms:

  17b-HSD10; ABAD; CAMR; DUPXp11.22; ERAB; HADH2; HCD2; MHBD; MRPP2; MRX17; MRX31; MRXS10; SCHAD

• Gene Name:

  Homo sapiens hydroxysteroid 17-beta dehydrogenase 10 (HSD17B10), transcript variant 1, mRNA.

• Gene ID:

  3028

• UniProt:

  Q99714

• Conjugation:

  Unconjugated

• Related Pathways:

  Alzheimer's disease, Metabolic pathways, Valine, leucine and isoleucine degradation

• Field of Research:

  Alzheimer's disease, Metabolic pathways, Valine, leucine and isoleucine degradation

• Dilution:

  WB 1:1000, IHC 1:50, IF 1:100, Flow 1:100

• Form:

  Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

• Buffer:

  Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

• Function:

  Druggable Genome

• Storage Conditions:

  Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

• Symbol:

  HSD17B10

• Overview:

  Carrier-free (BSA/glycerol-free) HSD17B10 mouse monoclonal antibody, clone LBI10B4

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/?term=3028

• Uniprot URL:

  https://www.uniprot.org/uniprot/Q99714