CRMP2 (DPYSL2) Mouse Monoclonal Antibody [Clone ID: LBI5D7]

• Background:

  This gene encodes a member of the collapsin response mediator protein family. Collapsin response mediator proteins form homo- and hetero-tetramers and facilitate neuron guidance, growth and polarity. The encoded protein promotes microtubule assembly and is required for Sema3A-mediated growth cone collapse, and also plays a role in synaptic signaling through interactions with calcium channels. This gene has been implicated in multiple neurological disorders, and hyperphosphorylation of the encoded protein may play a key role in the development of Alzheimer's disease. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Sep 2011]

• Synonyms:

  CRMP-2; CRMP2; DHPRP2; DRP-2; DRP2; N2A3; ULIP-2; ULIP2

• Gene Name:

  Homo sapiens dihydropyrimidinase like 2 (DPYSL2), transcript variant 2, mRNA.

• Gene ID:

  1808

• UniProt:

  Q16555

• Conjugation:

  Unconjugated

• Related Pathways:

  Axon guidance

• Field of Research:

  Axon guidance

• Dilution:

  WB 1:500~2000

• Form:

  Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

• Buffer:

  Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

• Function:

  Druggable Genome

• Storage Conditions:

  Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

• Symbol:

  DPYSL2

• Overview:

  Carrier-free (BSA/glycerol-free) DPYSL2 mouse monoclonal antibody, clone LBI5D7

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/?term=1808

• Uniprot URL:

  https://www.uniprot.org/uniprot/Q16555