ICOS Ligand (ICOSLG) Mouse Monoclonal Antibody [Clone ID: LBI2C5]

• Background:

  Ligand for the T-cell-specific cell surface receptor ICOS. Acts as a costimulatory signal for T-cell proliferation and cytokine secretion; induces also B-cell proliferation and differentiation into plasma cells. Could play an important role in mediating local tissue responses to inflammatory conditions, as well as in modulating the secondary immune response by co-stimulating memory T-cell function. [UniProtKB/Swiss-Prot Function]

• Synonyms:

  B7-H2; B7h; B7H2; B7RP-1; B7RP1; CD275; GL50; ICOS-L; ICOSL; LICOS

• Gene Name:

  Homo sapiens inducible T cell costimulator ligand (ICOSLG), transcript variant 1, mRNA.

• Gene ID:

  23308

• UniProt:

  O75144

• Conjugation:

  Unconjugated

• Related Pathways:

  Cell adhesion molecules (CAMs)

• Field of Research:

  Cell adhesion molecules (CAMs)

• Dilution:

  WB 1:2000, IHC 1:150

• Form:

  Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

• Buffer:

  Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

• Function:

  Transmembrane

• Storage Conditions:

  Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

• Symbol:

  ICOSLG

• Overview:

  Carrier-free (BSA/glycerol-free) ICOSLG mouse monoclonal antibody, clone LBI2C5

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/?term=23308

• Uniprot URL:

  https://www.uniprot.org/uniprot/O75144