Oxytocin neurophysin 1 (OXT) Mouse Monoclonal Antibody [Clone ID: LBI5G4]

• Background:

  This gene encodes a precursor protein that is processed to produce oxytocin and neurophysin I. Oxytocin is a posterior pituitary hormone which is synthesized as an inactive precursor in the hypothalamus along with its carrier protein neurophysin I. Together with neurophysin, it is packaged into neurosecretory vesicles and transported axonally to the nerve endings in the neurohypophysis, where it is either stored or secreted into the bloodstream. The precursor seems to be activated while it is being transported along the axon to the posterior pituitary. This hormone contracts smooth muscle during parturition and lactation. It is also involved in cognition, tolerance, adaptation and complex sexual and maternal behaviour, as well as in the regulation of water excretion and cardiovascular functions. [provided by RefSeq, Dec 2013]

• Synonyms:

  OT; OT-NPI; OXT-NPI

• Gene Name:

  Homo sapiens oxytocin/neurophysin I prepropeptide (OXT), mRNA.

• Gene ID:

  5020

• UniProt:

  P01178

• Conjugation:

  Unconjugated

• Dilution:

  WB 1:2000

• Form:

  Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

• Buffer:

  Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

• Function:

  Secreted Protein

• Storage Conditions:

  Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

• Symbol:

  OXT

• Overview:

  Carrier-free (BSA/glycerol-free) OXT mouse monoclonal antibody, clone LBI5G4

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/?term=5020

• Uniprot URL:

  https://www.uniprot.org/uniprot/P01178