Z-VDVA-(DL-Asp)-FMK

Z-VDVA-(DL-Asp)-FMK

• CAS Number: 1926163-61-2
• UNSPSC Description: Z-VDVA-(DL-Asp)-FMK is a Z-VDVAD-FMK derivative. Z-VDVAD-FMK (HY-P1008) is a special inhibitor of caspase-2[1].
• Target Antigen: Caspase
• Type: Peptides
• Related Pathways: Apoptosis
• Applications: Cancer-programmed cell death
• Field of Research: Cancer
• Assay Protocol: https://www.medchemexpress.com/z-vdva-dl-asp-fmk.html
• Solubility: 10 mM in DMSO
• Smiles: COC(CC(C(CF)=O)NC([C@H](C)NC([C@H](C(C)C)NC([C@H](CC(OC)=O)NC([C@H](C(C)C)NC(OCC1=CC=CC=C1)=O)=O)=O)=O)=O)=O
• Molecular Weight: 695.73
• References & Citations: [1]Gamen S, et al. Doxorubicin treatment activates a Z-VAD-sensitive caspase, which causes deltapsim loss, caspase-9 activity, and apoptosis in Jurkat cells. Exp Cell Res. 2000;258(1):223-235.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported