Z-VDVA-(DL-Asp)-FMK

• UNSPSC Description:

  Z-VDVA-(DL-Asp)-FMK is a Z-VDVAD-FMK derivative. Z-VDVAD-FMK (HY-P1008) is a special inhibitor of caspase-2[1].

• Target Antigen:

  Caspase

• Type:

  Peptides

• Related Pathways:

  Apoptosis

• Applications:

  Cancer-programmed cell death

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/z-vdva-dl-asp-fmk.html

• Solubility:

  10 mM in DMSO

• Smiles:

  COC(CC(C(CF)=O)NC([C@H](C)NC([C@H](C(C)C)NC([C@H](CC(OC)=O)NC([C@H](C(C)C)NC(OCC1=CC=CC=C1)=O)=O)=O)=O)=O)=O

• Molecular Weight:

  695.73

• References & Citations:

  [1]Gamen S, et al. Doxorubicin treatment activates a Z-VAD-sensitive caspase, which causes deltapsim loss, caspase-9 activity, and apoptosis in Jurkat cells. Exp Cell Res. 2000;258(1):223-235.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  1926163-61-2