Osteopontin (SPP1) Mouse Monoclonal Antibody [Clone ID: LBI6A12]

• Background:

  The protein encoded by this gene is involved in the attachment of osteoclasts to the mineralized bone matrix. The encoded protein is secreted and binds hydroxyapatite with high affinity. The osteoclast vitronectin receptor is found in the cell membrane and may be involved in the binding to this protein. This protein is also a cytokine that upregulates expression of interferon-gamma and interleukin-12. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2011]

• Synonyms:

  BNSP; BSPI; ETA-1; OPN

• Gene Name:

  Homo sapiens secreted phosphoprotein 1 (SPP1), transcript variant 1, mRNA.

• Gene ID:

  6696

• UniProt:

  P10451

• Conjugation:

  Unconjugated

• Related Pathways:

  ECM-receptor interaction, Focal adhesion, Toll-like receptor signaling pathway

• Field of Research:

  ECM-receptor interaction, Focal adhesion, Toll-like receptor signaling pathway

• Dilution:

  WB 1:2000

• Form:

  Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

• Buffer:

  Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

• Function:

  Druggable Genome, Secreted Protein

• Storage Conditions:

  Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

• Symbol:

  SPP1

• Overview:

  Carrier-free (BSA/glycerol-free) SPP1 mouse monoclonal antibody, clone LBI6A12

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/?term=6696

• Uniprot URL:

  https://www.uniprot.org/uniprot/P10451