IKZF3 Mouse Monoclonal Antibody [Clone ID: LBI7E11]

• Background:

  This gene encodes a member of the Ikaros family of zinc-finger proteins. Three members of this protein family (Ikaros, Aiolos and Helios) are hematopoietic-specific transcription factors involved in the regulation of lymphocyte development. This gene product is a transcription factor that is important in the regulation of B lymphocyte proliferation and differentiation. Both Ikaros and Aiolos can participate in chromatin remodeling. Regulation of gene expression in B lymphocytes by Aiolos is complex as it appears to require the sequential formation of Ikaros homodimers, Ikaros/Aiolos heterodimers, and Aiolos homodimers. Several alternative transcripts encoding different isoforms have been described, as well as some non-protein coding variants. [provided by RefSeq, Apr 2012]

• Synonyms:

  AIO; AIOLOS; ZNFN1A3

• Gene Name:

  Homo sapiens IKAROS family zinc finger 3 (IKZF3), transcript variant 1, mRNA.

• Gene ID:

  22806

• UniProt:

  Q9UKT9

• Conjugation:

  Unconjugated

• Dilution:

  WB 1:2000, IHC 1:150

• Form:

  Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

• Buffer:

  Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

• Storage Conditions:

  Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

• Symbol:

  IKZF3

• Overview:

  Carrier-free (BSA/glycerol-free) IKZF3 mouse monoclonal antibody, clone LBI7E11

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/?term=22806

• Uniprot URL:

  https://www.uniprot.org/uniprot/Q9UKT9