IKZF3 Mouse Monoclonal Antibody [Clone ID: LBI5E2]

• Background:

  This gene encodes a member of the Ikaros family of zinc-finger proteins. Three members of this protein family (Ikaros, Aiolos and Helios) are hematopoietic-specific transcription factors involved in the regulation of lymphocyte development. This gene product is a transcription factor that is important in the regulation of B lymphocyte proliferation and differentiation. Both Ikaros and Aiolos can participate in chromatin remodeling. Regulation of gene expression in B lymphocytes by Aiolos is complex as it appears to require the sequential formation of Ikaros homodimers, Ikaros/Aiolos heterodimers, and Aiolos homodimers. Several alternative transcripts encoding different isoforms have been described, as well as some non-protein coding variants. [provided by RefSeq, Apr 2012]

• Synonyms:

  AIO; AIOLOS; ZNFN1A3

• Gene Name:

  IKAROS family zinc finger 3

• Gene ID:

  22806

• UniProt:

  Q9UKT9

• Conjugation:

  Unconjugated

• Concentration:

  1 mg/ml

• Dilution:

  WB 1:2000, IHC 1:150

• Form:

  PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

• Buffer:

  PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

• Storage Conditions:

  Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

• Symbol:

  IKZF3

• Overview:

  Purified IKZF3 mouse monoclonal antibody, clone LBI5E2

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/?term=22806

• Uniprot URL:

  https://www.uniprot.org/uniprot/Q9UKT9