Prostate Specific Antigen (KLK3) Mouse Monoclonal Antibody [Clone ID: LBI2F3]

• Background:

  Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. Its protein product is a protease present in seminal plasma. It is thought to function normally in the liquefaction of seminal coagulum, presumably by hydrolysis of the high molecular mass seminal vesicle protein. Serum level of this protein, called PSA in the clinical setting, is useful in the diagnosis and monitoring of prostatic carcinoma. Alternate splicing of this gene generates several transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]

• Synonyms:

  APS; hK3; KLK2A1; PSA

• Gene Name:

  Kallikrein related peptidase 3

• Gene ID:

  354

• UniProt:

  P07288

• Conjugation:

  Unconjugated

• Related Pathways:

  Pathways in cancer, Prostate cancer

• Field of Research:

  Pathways in cancer, Prostate cancer

• Concentration:

  1 mg/ml

• Dilution:

  WB 1:2000, IHC 1:150

• Form:

  PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

• Buffer:

  PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

• Function:

  Druggable Genome, Protease, Secreted Protein

• Storage Conditions:

  Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

• Symbol:

  KLK3

• Overview:

  KLK3 mouse monoclonal antibody, clone LBI2F3

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/?term=354

• Uniprot URL:

  https://www.uniprot.org/uniprot/P07288